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Drug Discovery Approach

NGM’s drug discovery approach integrates sophisticated bioinformatics capabilities, relevant in vivo disease models and a rapid system to assess the physiological activity of prospective targets in laboratory disease models. This strategy is different from conventional discovery platforms that are solely based on in vitro or ‘test tube’ experiments, and often generate results that do not correlate with human biological activity. We have identified peptide, protein and antibody targets with intriguing biological effects and are actively pursuing drug candidates for development.