A Progressive Retinal Degenerative Disease,
A Significant Unmet Need
Age-related macular degeneration is a leading cause of vision loss and blindness in people over the age of 65 in the US and other industrialized countries. The two advanced stages of the disease are called neovascular (wet) AMD and geographic atrophy (GA).
GA is a progressive retinal degenerative disease associated with irreversible loss of vision, diminished quality of life and eventual blindness. GA is estimated to impact about 1 million people in the US and over 5 million people worldwide.
In patients with GA, single or multiple areas in the macular region of the retina become atrophic, forming distinct lesions that expand and coalesce over time. Enlargement of these lesions can lead to loss of vision and irreversible blindness. GA is often bilateral, meaning it occurs in both eyes.