OUR MISSION
To translate complex powerful biology with urgency and rigor to deliver life-changing medicines
View our pipeline of novel investigational medicines spanning multiple therapeutic areas.
Powerful Biology. Novel Medicines. Transformative Impact.
OPHTHALMOLOGY PROGRAM
NGM621's potential: reducing disease progression in geographic atrophy (GA)
GA is a progressive retinal degenerative disease
impacting over 5 million people worldwide.
Powerful Biology. Novel Medicines. Transformative Impact.
ONCOLOGY PROGRAM
NGM120 is in Phase 2 study for the treatment of metastatic pancreatic cancer and cancer-related cachexia
Cachexia is a severe muscle-wasting syndrome.
Powerful Biology. Novel Medicines. Transformative Impact.
ONCOLOGY PROGRAM
NGM707 is a novel antagonist antibody inhibiting both ILT2 and ILT4
ILT2 and ILT4 may serve as checkpoints that enable tumors to evade immune detection.
Powerful Biology. Novel Medicines. Transformative Impact.
ONCOLOGY PROGRAM
NGM438 is a novel antagonist antibody inhibiting LAIR1
LAIR1 may form a stromal checkpoint that impedes anti-tumor immunity.
Powerful Biology. Novel Medicines. Transformative Impact.
BECOME AN NGMer
We love working together and challenging each other to pursue great science that will deliver a big impact for patients.
Curious, creative and driven to make a difference?
Consider NGM to advance your career!
OUR PIPELINE
We aspire to operate one of the most productive R&D engines in the biopharma industry.
Our broad, diverse pipeline of novel, first-in-class medicines spans multiple therapeutic areas and diseases. Every program focuses on a large market indication with high unmet needs and a common goal: delivering outsized impact for patients.
We have built our company around core scientific values that frame our approach to drug discovery and development.
Our Core ValuesLatest News
NGM621 for Geographic Atrophy (GA)
NGM621, our anti-complement C3 antibody, is currently in Phase 2 study (CATALINA) as a treatment to potentially reduce disease progression in patients with GA and with the potential for every eight week dosing.
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Working Here
Our People Are Our Platform.
What makes NGM tick? Really smart team members who love working together to pursue great science and share a common drive to deliver a huge impact for patients. We have no hierarchies. We collaborate intensively, embrace risk freely and always swing for the fence.
Join Us